After 11 years and over 350 appearances in all competitions, Ramsey will join Juventus from July 1 on a four-year-deal as free agent.
He will earn around £400,000 per week, which will make him the highest-paid British player of all time.
And in a statement on the club’s website, Arsenal hailed his contribution to the club.
Arsenal said: “Everyone at Arsenal Football Club wishes Aaron Ramsey a happy and successful future.
“Aaron’s made a fantastic contribution to our club since joining from Cardiff City in 2008.
“He has always been a consummate professional and will always have a special place in the hearts and memories of Arsenal fans around the world.
“We look forward to Aaron helping the team to a strong end to this season before he joins Juventus in the summer.”
In a statement posted on his social media accounts, Ramsey thanked Arsenal fans and vowed to give 100 per cent for the club until he leaves in the summer.
Ramsey wrote: “As you may have already heard, I have agreed a pre-contract with Juventus Football Club.
“I wanted to issue a personal statement for all the Arsenal fans who have been extremely loyal and supportive.
“You welcomed me as a teenager and have been there for me through all the highs and lows I’ve encountered during my time at the club.
“It is with a heavy heart that I leave after 11 incredible years in North London. Thank you.
“I will continue to give the team 100 per cent and hope to finish the season strongly, before heading on to my next chapter in Turin. Kind regards, Aaron.”
Former Wales international, Iwan Roberts, accused Arsenal fans of not appreciating Ramsey enough.
“They haven’t appreciated him from the first day he walked through the door,” he said.
“We [in Wales] would rather see him go to Juventus. He could do with a fresh start.”
While Ramsey’s former Wales team-mate Danny Gabbidon has backed the midfielder to add extra quality to Juventus.
“If you look at Juventus and the make-up of their midfield, he will bring something that they don’t have,” says Gabbidon.
“They have Emre Can, Sami Khedira, Miralem Pjanic, Blaise Matuidi – none of those are players who get in the box and have that goalscoring threat, so I’m sure that’s why Juve have identified him.
“Juve are dominant so if he goes there he’s going to be winning league titles, but Serie A is becoming more competitive with Napoli and Inter Milan competing again.”